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What are stress hormones?

If you’ve ever noticed that a stressful week is followed by a flare-up, you’re not imagining it. Stress plays a real and measurable role in how autoimmune diseases behave—and it often starts with hormones like cortisol and adrenaline.

When your brain senses danger or pressure—whether physical or emotional—it triggers a stress response. This floods your body with hormones designed to help you act quickly and survive. But when stress becomes chronic, the body stays in that activated state for too long.

How stress hormones impact inflammation

Cortisol is supposed to help control inflammation. But when it’s released constantly, the system gets worn out. Over time, this leads to:

• Increased inflammation throughout the body
• Weakened immune regulation, which can trigger flares
• Disrupted sleep and digestion, which affect symptom control
• Higher fatigue and brain fog

Recognizing stress-driven flares

If your flares often follow major life events, poor sleep, or emotional exhaustion, stress hormones may be playing a role. Common patterns include:

• Morning stiffness that lingers
• A sudden return of symptoms without a clear cause
• Increased pain, fatigue, or mood swings

Supporting your stress response

• Try daily breathing exercises, even just 5 minutes
• Create routines that include both rest and movement
• Get outside or into sunlight when possible
• Say no to tasks that drain your energy
• Talk with your provider about flare planning and mental health support

Your body needs calm to heal

Stress may be part of life, but managing it doesn’t mean ignoring it. It means finding tools that support your nervous system and lower the pressure on your immune system. Small changes can help break the stress-flare cycle and give your body space to recover.

Your Symptoms Matter

If you’re ready to take the next step toward clarity and relief, the team at AMS Rheumatology in Amarillo is here to walk with you, providing compassionate care, expert guidance, and personalized treatment plans designed to help you regain control, reduce discomfort, and improve your quality of life.